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MMR vaccine: How it works and when it’s recommended

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June 8, 2025
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Over the years, scientists have developed groundbreaking vaccines which have considerably lowered and prevented the unfold of extremely contagious illnesses worldwide.

One such vaccine is the measles, mumps and rubella (MMR) vaccine. In truth, the MMR vaccine is the explanation why measles, mumps and rubella are a lot much less frequent within the United States at the moment.

Below, we’ll clarify what the MMR vaccine is and what it protects in opposition to. We’ll additionally go over the MMR vaccine schedule for kids and adults, potential unwanted side effects and why it’s so necessary to get vaccinated.

What is the MMR vaccine and how does it work?

The MMR vaccine is a live-attenuated vaccine, which implies it comprises a small quantity of weakened measles, mumps and rubella (German measles) viruses. The first vaccines to guard in opposition to measles, mumps and rubella have been developed within the Nineteen Sixties and given as particular person photographs. Then within the Seventies, scientists launched a mixed MMR vaccine to guard in opposition to all three illnesses.

Today, there are two MMR vaccine formulations:

  • MMR vaccine – Protects in opposition to measles, mumps and rubella
  • MMRV vaccine – Protects in opposition to measles, mumps, rubella and varicella (hen pox), and it’s solely accredited to be used in kids 12 months to 12 years outdated

The MMR vaccine is the recommended formulation by the Centers for Disease Control and Prevention (CDC) as a result of the MMRV vaccine has been related to a barely increased danger for fever and febrile seizures after vaccination. There’s a separate vaccination for defense from varicella.

How the MMR vaccine works

Like all vaccines, the MMR vaccine prompts your immune system and teaches it how you can battle sure germs with out you getting sick. Despite some vaccine myths, a live-attenuated vaccine can’t offer you any of the illnesses it protects in opposition to. Most folks obtain two doses of the MMR vaccine, which maximizes long-term immunity.

How efficient the MMR vaccine is at stopping sickness

According to the CDC, one dose of the MMR vaccine is:

  • 93% efficient in opposition to measles
  • 72% efficient in opposition to mumps
  • 97% efficient in opposition to rubella

Two doses of the MMR vaccine is:

  • 97% efficient in opposition to measles
  • 86% efficient in opposition to mumps

Because rubella was declared eradicated within the U.S. in 2004, there aren’t many research accessible about how efficient a second dose of MMR is at defending in opposition to rubella.

While it continues to be potential to contract measles, mumps and rubella from an contaminated person even in case you’re vaccinated in opposition to them, it’s extraordinarily uncommon. And in case you do get any of the illnesses, it probably received’t be a critical case or trigger critical issues.

How lengthy does the MMR vaccine shield you?

If you’ve obtained the total vaccine schedule, you’re thought-about protected for all times in opposition to measles and rubella, and most likely wouldn’t contract both an infection if uncovered to it. While the MMR vaccine supplies extremely efficient safety in opposition to mumps, research have proven that your immunity could lower over time, and you is probably not protected in opposition to mumps in case you’re uncovered to it later in life.

Why it’s necessary to get the MMR vaccine

As with any vaccine, the advantages of the MMR vaccine enormously outweigh the dangers related to contracting measles, mumps or rubella.

For instance, earlier than the nationwide measles vaccination program started within the U.S. within the Nineteen Sixties, almost each person had measles earlier than maturity, with round half 1,000,000 reported instances per yr. Most individuals who had it recovered with out long-term unwanted side effects. But others skilled long-term unwanted side effects or needed to be hospitalized, and many died from issues of the illness.

Due to the success of the vaccine program, measles was declared eradicated within the U.S. by the yr 2000. Deaths resulting from issues from measles dropped from round 500 annually to a few recorded instances from 2000-2024. However, scientists have seen outbreaks of measles instances within the U.S. in recent times resulting from quite a few components, the largest being vaccine hesitancy.

Data exhibits that about 1 in 5 unvaccinated folks will must be hospitalized in the event that they contract measles. In addition, measles can result in extra extreme points equivalent to pneumonia and encephalitis (swelling within the mind), and statistics have proven that 3 folks out of 1,000 will die, even with the very best care potential. So, it’s necessary to get the vaccine to guard your self from preventable sickness.

And whereas there was an over 99% lower in reported mumps and rubella instances because the Nineteen Sixties because of the MMR vaccine, outbreaks can nonetheless happen, so it’s nonetheless an important a part of the vaccine to maintain you protected.

How protected is the MMR vaccine?

The MMR vaccine has been examined rigorously worldwide, administered to hundreds of thousands of individuals and confirmed to be protected. It’s the simplest approach to shield your self and your kids in opposition to sickness and critical issues from preventable illnesses.

While many individuals get well, others can expertise issues from these viral infections that vary from delicate to life threatening.

The MMR vaccine can’t trigger autism

Autism spectrum dysfunction (ASD) is a developmental dysfunction that continues to be studied extensively. In these research, it’s been decided that there is no such thing as a hyperlink between receiving vaccinations and creating ASD. Additionally, there aren’t any hyperlinks discovered between the components in vaccines and ASD.

The MMR and different vaccines don’t improve the danger of creating autism, and don’t set off autism in kids. The typical unwanted side effects are uncommon and delicate, and it’s a lot safer to get the vaccine than danger potential sickness.

Who ought to get the MMR vaccine and when

The MMR vaccine is part of the recommended vaccine schedule for kids, and it’s a protected and efficient approach to shield in opposition to extremely contagious measles, mumps and rubella infections.

The CDC recommends that everybody get the MMR vaccine in the event that they’re capable of, however the suggestions for what vaccine to get and when are completely different for adults, teenagers and kids.

It’s necessary to maintain your youngster present on their vaccination schedule to guard them in opposition to preventable sicknesses. The MMR vaccine is a part of that schedule, and the CDC recommends:

  • The first dose when your youngster is 12 to fifteen months outdated
  • The second dose when your youngster is 4 to six years outdated

Under particular circumstances, it’s potential to your youngster to get their second dose earlier, so long as it’s given at the very least 28 days after their first. If your youngster is touring internationally, or if there’s a native outbreak of measles or mumps in your group, the CDC recommends following the minimal interval of 28 days.

For kids ages 12 months to 4 years outdated, the MMR and MMRV vaccines are each choices, however converse along with your physician about which vaccine is true to your youngster.

For kids who’re 4 years and older, each MMR and MMRV are choices. The CDC recommends that:

  • If MMR is given as a primary dose, the popular second dose is MMRV
  • If MMRV is given as a primary dose, MMRV is the popular second dose over separate MMR and varicella vaccines

If your youngster will get MMRV as their first vaccine, they need to obtain the second MMRV vaccine at the very least three months after the primary.

MMR vaccine schedule for teenagers

For teenagers older than 12 years outdated who’ve obtained each doses of MMR, there’s no want for extra doses.

For teenagers older than 12 years outdated who weren’t vaccinated as kids, the CDC recommends each MMR doses, at the very least 28 days aside.

For teenagers who’re going into post-high college establishments, like a school or college, many vaccines could also be required, together with the MMR vaccine. If they didn’t obtain the vaccine when they have been youthful, it’s recommended they get each MMR doses, at the very least 28 days aside. Once they’ve obtained each doses, there’s no want for a booster.

MMR vaccine schedule for adults

Adults who can present immunity to measles, mumps and rubella, as a result of they’ve both been totally vaccinated or that they had measles, mumps and rubella in some unspecified time in the future of their lives, don’t want an MMR vaccine dose at any time.

Adults who didn’t have measles, mumps or rubella at any level of their lives or are not sure in the event that they’re totally vaccinated ought to obtain at the very least one dose of the MMR vaccine. Certain adults at higher danger of measles and mumps might have two doses at the very least 28 days aside if:

  • They’re a scholar, college member or a part of the employees at a post-high college establishment
  • They work in a health care setting
  • They’re touring internationally

Possible unwanted side effects of the MMR vaccine

Most folks don’t expertise unwanted side effects from the MMR vaccine, but when they do, unwanted side effects are normally delicate. If you do expertise these delicate unwanted side effects, it’s an indication out of your immune system that the vaccine is working. Side results can embody:

  • Fever
  • Mild rash
  • Pain on the injection website
  • Temporary stiffness or ache within the joints, notably in teenagers and grownup women who didn’t have already got immunity to the rubella a part of the vaccine
  • Swelling within the cheeks or neck (very uncommon)
  • Low platelet rely (very uncommon)

Extremely hardly ever, a person may need a critical allergic response to the MMR vaccine. If you do expertise a critical response, like anaphylaxis or issue respiratory, name 911 instantly.

The MMRV vaccine has been linked to a really small danger of febrile seizures, that are seizures brought on by a fever, however it’s extraordinarily uncommon and doesn’t trigger long-term unwanted side effects.

Since the danger of febrile seizures will increase as kids become old, it’s recommended they observe the MMR vaccine schedule and get vaccinated as quickly as they’re in a position.

And lastly, if in case you have an allergic response to any element of the vaccine, or a critical allergic response to the antibiotic neomycin (which is within the vaccine), you shouldn’t get the vaccine.

Protect your self from measles, mumps and rubella

The CDC and most medical professionals advocate getting the MMR vaccine. Vaccines just like the MMR vaccine supply the very best safety in opposition to extremely contagious but preventable illnesses, so converse along with your physician to find out if or when you or your youngster ought to obtain it.

If you recognize you or your youngster haven’t been vaccinated in opposition to MMR, or in case you’re not sure of your MMR vaccination standing, converse to your physician about subsequent steps. And in case your youngster is due for his or her MMR shot, make an appointment to get the vaccine. It’s necessary to your youngster’s health to be updated on all recommended vaccinations.

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